Does anyone know anything about drusens when they are the sole cause of legal blindness?


Question:
The drusens are not a part of retinitis pigmentosa.

Answers:
Drusens are rarely seen clinically before 45 years, but they are universal after age 60. There are two types of macular degeneration: Ninety percent of people with macular degeneration have the dry type, in which small, yellow spots called drusens form underneath the macular. Drusens are believed to be waste products that accumulate because of lack of antioxidants to clear the waste from the eyes The drusen slowly break down the cells in the macular, causing distorted vision. Dry macular degeneration can progress to the second, more severe type, called wet macular degeneration.

In the wet type, new, abnormal blood vessels begin to grow toward the macular, causing rapid and severe vision loss. What would you like to know?

Drusens are thought to be by-products of the retinal rigment epithelium (RPE) which
couldn't be cleared and recycled.

They accumulate in the Bruchs membrane just underneath the RPE. They appear as yellow excrescences in the posterior pole on ophthalmoscopy.




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