Is there a link between manic depression and schizofrenia?
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Despite the fact that schizophrenia and bipolar disorder have different diagnostic credentials in the bible of American psychiatric medicine (the DSM-IV), the two disorders show a significant overlap of symptoms, as well as some similar treatment strategies. Now, scientists are discovering some of the key biological similarities that may link these diseases even more strongly.
A new study reported in The Lancet (2003;362:798-805) has found a genetic link between schizophrenia and bipolar disorder.
Researchers performed clinical studies on 15 brains affected by schizophrenia, 15 affected by bipolar disorder, and 15 with neither. Tests were performed to determine what genes are expressed in each. The research revealed similarities in the reduction of oligodendrocyte-related and myelin-related genes. The researchers also found similar expression changes to the schizophrenia group in bipolar brains, which thus lends support to the notion that the disorders share common causative and pathophysiological pathways.
Other Answers:
the link is both dont exist .. check this website out read the article to the end please its v important .. http://www.antipsychiatry.org/schizoph.htm and .. http://www.oikos.org/biopsychiatry.htm
There is not really a very clear line between any mental illnesses. While we have learned a lot about the brain over the past few decades, there is still a lot we do not know, and a lot of gray area. You have to think of diagnoses on a sliding scale more than clearly defined categories. Manic depression and schizophrenia are very much alike in their symptoms: mood swings, irrational thought patterns, paranoia. Treatment that is effective for one disorder might be used with success to treat symptoms of someone with another disorder. The difference is that bipolar is characterized by a greater degree of mood swings, while schizophrenia is characterized more by hallucinations, irrational thought patterns and paranoia. There is not as much of a chance in one BECOMING the other as much as doctors changing the diagnoses in order to more effectively facilitate treatment.
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