anyone on olanzapine/divalproex... what can u expect on the first day of use?
Question:
Answers:
You're gonna be out of it dude.
Other Answers:
sleep.. oh and more sleep.. and don't drive
first you might gain weight; then you might have 'td" tardive dysenia adnormal muscle stiffness or movement
and yes drowsness!
Side effects Of olanzapine
Dizziness, somnolence, dry mouth, dyspepsia, constipation, ALT (SGPT) increased, personality disorder, increased appetite, weight gain, akathisia, asthenia, tremor, postural hypotension. Rare cases of Priapism and leukopenia.
Interactions:
May enhance the effects of alcohol, centrally-acting drugs, antihypertensive agents; may antagonize the effects of levodopa and dopamine agonists. Decreased levels of olanzapine with carbamazepine, omeprazole. Inhibitors of olanzapine's metabolism: fluvoxamine, ciprofloxacin, ketoconazole. Concomitant smoking may increase olanzapine's metabolism.
Side effects of divalproex:
Epilepsy:
The most commonly reported adverse reactions are nausea, vomiting and indigestion. Since valproic acid has usually been used with other antiepileptics, it is not possible in most cases to determine whether the adverse reactions mentioned in this section are due to valproic acid alone or to the combination of drugs.
Gastrointestinal:
Nausea, vomiting and indigestion are the most commonly reported side effects at the initiation of therapy. These effects are usually transient and rarely require discontinuation of therapy. Diarrhea, abdominal cramps and constipation have also been reported. Anorexia with some weight loss and increased appetite with some weight gain have also been seen.
CNS:
Sedative effects have been noted in patients receiving valproic acid alone but are found most often in patients on combination therapy. Sedation usually disappears upon reduction of other antiepileptic medication. Ataxia, headache, nystagmus, diplopia, asterixis, "spots before the eyes", tremor (may be dose-related), dysarthria, dizziness, and incoordination have rarely been noted. Rare cases of coma have been reported in patients receiving valproic acid alone or in conjunction with phenobarbital.
Dermatologic:
Transient increases in hair loss have been observed. Skin rash, photosensitivity, generalized pruritus, erythema multiforms, Stevens-Johnson syndrome and petechiae have rarely been noted.
Endocrine:
There have been reports of irregular menses and secondary amenorrhea, breast enlargement, galactorrhea and parotid gland swelling in patients receiving valproic acid. Abnormal thyroid function tests have been reported .
Use this as a reference guide only...you may not experience any of the above.
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