Antidepressant effect of Chlorpheniramine?

Question: Is it serotonergic? How much Chlorpheniramine is equal to Fluoxetine 10mg? Which are the neurotransmitters affected? Does this drug help in withdrawal symptoms of SSRIs? Detailed information of Chlorpheniramine related with Neuropsychiatry will be appreciated.
Please give me web addresses that give information related to this.

Answers:
Chlorphenamine has antidepressant properties, inhibiting reuptake of the neurotransmitter serotonin. Based on this knowledge, the Swedish company Astra AB was able to derive the first marketed selective serotonin reuptake inhibitor, zimelidine, from chlorphenamine.

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Chlorphenamine has antidepressant properties, inhibiting reuptake of the neurotransmitter serotonin. But its is mostly used as a antihistamine and not as a anti depressant, and it is a SSRI!!

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