what does the drug phenotab cure?
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Phenotab is made my WILSHIRE LABORATORIES (PVT) LTD and is a PHENOBARBITONE. Phenobarbitone is a barbiturate that is mainly used for its antiepileptic properties. Phenobarbitone acts as a nonselective depressant of the central nervous system capable of producing all levels of CNS mood alteration from excitation to mild sedation, hypnosis and deep coma. In sufficiently high doses, barbiturates induce anaesthesia. Recent studies have suggested that the sedative-hypnotic and anticonvulsant effects of barbiturates may be related to their ability to enhance and/or mimic the inhibitory synaptic action of gamma-aminobutyric acid (GABA). Anticonvulsant - Barbiturates are believed to act by depressing monosynaptic and polysynaptic transmission in the CNS. They also increase the threshold for electrical stimulation of the motor cortex. Antihyperbilirubinemic - Phenobarbital lowers serum bilirubin concentrations probably by induction of glucuronyl transferase, the enzyme which conjugates bilirubin. Barbiturates have little analgesic action at subanaesthetic doses and may increase reaction to painful stimuli. Barbiturates have been shown to reduce the rapid eye movement (REM) phase of sleep or dreaming stage. Also, Stages III and IV sleep (slow-wave sleep, SWS) are decreased. Animal studies have shown that barbiturates cause reduction in the tone and contractility of the uterus, ureters, and urinary bladder; however, concentrations required to produce this effect in humans are not attained with sedative-hypnotic doses. Barbiturates have been shown to induce liver microsomal enzymes, thereby increasing and altering the metabolism of other medications or compounds. If you would like more information, this is the only like I could find any useful information at.
http://www.medsafe.govt.nz/Profs/Datasheet/p/Phenobarbitonetab.htm
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