What is nesidioblastomi.


Question:
It's disease of some kind, but I am not sure what it is.

Answers:
nesidioblastosis
Nesidioblastosis is a controversial medical term for hyperinsulinemic hypoglycemia attributed to an abnormal microscopic appearance of pancreatic islet development. The term was coined in the first half of the 20th century. The abnormal histologic aspects of the tissue included the presence of islet cell enlargement, islet cell dysplasia, beta cells budding from ductal epithelium, and islets in apposition to ducts.

By the 1970s, nesidioblastosis was primarily used to describe the pancreatic dysfunction associated with persistent congenital hyperinsulinism and in most cases from the 1970s until the 1970s, it was used as a synonym for what we now refer to as congenital hyperinsulinism.

The term fell into disfavor after it was recognized in the late 1980s that the characteristic tissue features were sometimes seen in pancreatic tissue from normal infants and even adults, and is not consistently associated with hyperinsulinemic hypoglycemia. Most congenital hyperinsulinism is caused by different mechanisms than excessive proliferation of beta cells in a fetal pattern.

A small number of case reports have purported to describe nesidioblastosis in adults

Other Answers:
nesidioblastoma..A benign tumor(cancer) of the islets of Langerhans that may occur anywhere throughout the pancreas. Such tumors may result in HYPERINSULINISM or ZOLLINGER-ELLISON SYNDROME.

It causes opposite effects of Diabetes, as there will be lot of INSULIN
Source(s):
Dr AB

Nesidioblastoma.

A benign tumor of the islets of Langerhans that may occur anywhere throughout the pancreas. Such tumors may result in HYPERINSULINISM or ZOLLINGER-ELLISON SYNDROME. These tumors affect the cells that make insulin, so symptoms include those of hypoglycemia: Weakness, dizzyness, confusion, etc.

Read more about it in the links below.
Source(s):
http://www.emedicine.com/ped/topic1565.htm



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