how we can diagnosis of H5N1 IN LABORATORY?

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Samples should be collected within the first 4 days of illness. Rapid influenza tests provide results within 24 hours; viral culture provides results in 3-10 days. Most of the rapid tests that can be done in a physician's office are approximately >70% sensitive for detecting influenza and approximately >90% specific. Thus, as many as 30% of samples that would be positive for influenza by viral culture may give a negative rapid test result. And, some rapid test results may indicate influenza when a person is not infected with influenza.

Serum samples also can be tested for influenza antibody to diagnose recent infections. Two samples should be collected per person: one sample within the first week of illness and a second sample 2-4 weeks later. If antibody levels increase from the first to the second sample, influenza infection likely occurred. Because of the length of time needed for a diagnosis of influenza by serologic testing, other diagnostic testing should be used if a more rapid diagnosis is needed.

During outbreaks of respiratory illness when influenza is suspected, some samples should be tested by both rapid tests and by viral culture. The collection of some samples for viral culture is essential for determining the influenza subtypes and strains causing illness, and for surveillance of new strains that may need to be included in the next year's influenza vaccine. During outbreaks of influenza-like illness, viral culture also can help identify other causes of illness when influenza is not the cause.

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how we can diagnosis of H5N1 IN LABORATORY?

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