Do certain anti depressants make you more sleepy than others?


I seem to be more tired and still don't sleep well. Is because I'm on zoloft?

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Answers:
Yes Zoloft can make you tired. I previously took Effexor SR 150mg. and it would make me tired. See if you Dr. will allow you to take your medications at night. I did that and it helped. Don't forget, depression also makes us tired, so the two combined does not help. I know from many years of fighting depression, it's a hard battle and my heart goes out to you. If you need to ask questions direct, I believe you can get me through this system. I find I can sleep better in the daytime better than at night, which I am sure that's another great feature of avoidance. Hope you start feeling better. Di

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The anti depressants can have different reactions on the body. So yes some can make you more sleepy then others depending on your bodies chemical reaction to them.
Source(s):
Personal experience

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One of the common side effect of Zoloft is feeling sleepy and not sleeping well, I have never taken this Selective Serotonin Reuptake Inhibitor but the others that I have taken have caused me those type of side effects to start with, then over time say 3 - 6 months the effects slowly reduces. I have tried about four different types and each one has about the same effect.

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There is more to it than one antidepressant. Most work better in a combination form. And yes some do make you more tired (sleepy) than others. But the best thing to do is to see if you doctor will give you a mood stabilizer to go along with your anti depressant. The two will help you sleep well or at least better than you are now.

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I take 150 mg. of Zoloft everyday for 2 years.
Yes,it can make you sleepy.
Prior to that, I was taking 100 mg. of Effexor XR and it had just the opposite effect, it made me wired throughout the day, and I had to take Ativan constantly.
You didn't mention how long you had been on Zoloft, when I first started it, I went straight from the Effexor to 50mg. of Zoloft for a week, then 100 mg. for months, then doc increased it to 150mg., so I have been on 150mg. for about 11/2 years.
When I was on Effexor, I still was having panic attacks and anxiety a lot, Zoloft works much better for me, and I finally found the dosage I need to maintain.
I talked my friend into changing from Paxil to 50 mg. of Zoloft about 8 months ago and her anxiety is also much better.
Hang in there,usually the sleepiness gets better after about 4-6 weeks when you adjust to it.
Good luck to you,hope you feel better!


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