Chronic Myeloid Leukemia?

Question:

Ok.. just a couple quick questions- recently a member of my family was diagnosed with this disease. as of right now here white blood cells are normal but she has an extremely high platelet count. They have already done a bone marrow test- and she has the philadelphia chromosome. Does this make sense to anyone out there? Shouldnt her white blood cells be way to low/high as well

Answers:
In Chronic Myeloid Leukemia, normal blood cell production is completely replaced by leukemic cells, which however still function normally. It can occur at any age but the peak incidence is at the age of 40-60 yrs. The only predisposing factor is irradiation like in patients who receive radiotherapy. The most characteristic feature of this disease is the demonstration of Philadelphia chromosome in the leukemic blasts ( Ph-positive ) which is present in over 95% of cases. The Total leukocyte count -above 30x10to the power of 9 per litre. 1. Initial Chronic Phase : Symptoms are alleviated by treatment. 2.Phase of transformation: Disease becomes more aggressive with enlarging spleen, rising leucocyte count or rising proportion of blast cells in peripheral blood and Ph Chromosome. Bone Pain and haemorrhages from various sites. In about 20% transformation occurs abruptly.

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Chronic Myeloid Leukemia?

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