Is it possible for the same parents to bear two children: one with blood type 0, the other with AB?

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Answers:
First, let's look at the ABO blood types. Each person receives an A, B, or O gene from each parent. In this system, the A and B genes are co-dominant and the O gene is recessive. Thus, a person whose genetic type is either AA or AO will have blood type A, those with genetic type BB or BO will have blood type B, and only those genetic type OO will have blood type O. This means that a child with type O blood could have parents with type A, type B, or type O blood (but not with type AB). Conversely, if two parents both have type O blood, all their children will have type O blood.

Another medically important blood type is described in the Rh system. These genes were first discovered in the rhesus monkey, hence the designation Rh. The Rh system is actually far more complex than the ABO system in that there are 35 different possibilities that one could inherit from each parent. These, however, are roughly grouped into positive and negative types. In this system the positive are dominant over the negative. If your genetic type is ++ or +-, your blood type will be Rh positive. Only if your genetic type is -- will you be Rh negative. This means that if both parents have Rh+ blood with the +- genes, they could have children who are ++, +-, or --. In other words, their children could be either Rh positive or Rh negative. Children who are Rh negative can have parents who are either Rh positive or Rh negative.

Two parents who have O positive blood could easily have a child who is O negative. In fact, most children who are O negative have parents who are positive, since the +- combination is so much more common than the -- combination.

As it turns out, there are more than a dozen complete blood group systems other than the ABO system and the Rh system. This makes great precision possible in looking at inheritance and family trees.

There is no reason, based on your blood type, to suspect that your parents might not really be your parents. If questions linger for other reasons, specific tests are available through blood banks that can settle the issue. Given the billions of unique people on this planet, the power and precision of genetic testing are amazing.

Other Answers:
yes, but it depends on both of the parents genes.

i made a punnet square - the parents would have to have AO and BO blood type for this to happen. So yes I see no reason why not.

Yes, it's not uncommon.

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Is it possible for the same parents to bear two children: one with blood type 0, the other with AB?

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