My brother has polycystic kidneys. It runs in our family. My mother died from them.?

Question:

He has asked me to consider donating a kidney. I have completed the frist blood work, typing and we have compatible types. I have a daughter and grand-daughter as well.
I was told that if I didn't carry the gene I could donate. Upon considering this; Am I being selfish to say no to my brother if there is a chance that my daughter or grand-daughter may need a kidney since it runs in the family?

Answers:
That is a tough question! And unfortunately one only you must answer. All I can do is give an opinion.

First, I want to commend you for trying to see into the futures of your daughter and grandchild and wanting them to have long healthy lives.

You didn't state if you actually carried the gene for polycystic kidneys. I've read that if one of your parents have PKD each child has a 50% chance of carrying and developing the disease. Pregnant women with PKD will have problems. If this did not occur with your pregnancy, chances are good that your daughter does not have the disease. If you don't carry that gene, chances are, your daughter and granddaughter do not carry that gene.

One of the ways they check for PDK is a sonogram. From personal experience of sonograms, that test is easy, it's simple and relatively quick. I got to watch while they checked my kidneys. It is such a relief to know. PKD generally "hits" around middle age and again in the 60 year old range. If you are an older person, will you still be around when she reaches middle age?

If you do carry that gene, not only can you not donate to your brother, you cannot donate to your offspring.

I'm sorry I could not give you a definitive answer. There are none at this point. More testing is needed.

This is a difficult time. Good Luck in testing.

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My brother has polycystic kidneys. It runs in our family. My mother died from them.?

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