Can I take Acetaminophen with Codeine with Ibuprofen?


Question:
The Pharmacist I spoke to said "I'm not sure, I will call back." .... That didn't reassure me much, and he hasn't called back in quite some time. My doctor said I could take more than one of the A/C's but I would rather supplement with something non-narcotic if possible.

Answers:
Please note that these are general guidelines, not as substitution for Doctor’s consultation.

Take either Or. Never both together or a mix of the two as the dosage of each Not given above, when taken together, do so under Doctor’s recommendation:

- Codeine - painkiller, Acetaminophen - anti-inflammatory. (3)(‘Precautions While Using This Medicine’, Medline Plus)
- Ibuprofen - anti-inflammatory (2) & Fever reduction. Howver, Ibuprofen contains aminoglycosides that may lead to excessive thinning of the blood and subsequent bleeding if taken in the wrong combinations. (4) (‘DRUG INTERACTIONS’, Ibuprofen Primer.)

- Codeine does not accumulate in body tissues. It is excreted in urea and feces with 24 hours of consumption. Its analgesic effect tends to peak within 1 to 3 hours and persists between 4 and 6 hours. (1) (subheader – Pharmacokinetics)

- 85% of acetaminophen is discharged through urea within 24 hours.
It acts as an ancillary analgesic once the codeine wears off. (1)(– Pharmacokinetics)

Some prescribed single adult dosage is: (1) (subheader – Dosage and Administration)
Codeine Phosphate - single dose15 mg to 60 mg // 360 mg maximum dose over 24 hours
Acetaminophen - 300 mg to 1000 mg // 4000 mg 24 hours

Barring your prior medical history and allergies, one’s personal experience is to complete the one to two days prescription.

Should discomfort and swelling persist, Doctor’s consultation or a specialist on the next day should be sought or immediately after the course. Ibuprofen is in no way an adequate substitute for Codeine.

Prevention and reduction of Liver, Kidney and Urinary tract infection.
- Increasing intake of water to at least eight glasses of water or up to three litres a day will help minimize liver and kidney damage. Frequent toilet visitations to be expected.
- Pure cranberry juice and blueberry juice helps to minimize infections and has high antioxidants that work against free radicals. ( Especially with female tract infection. )

Gentle reminder: These recommendations are no substitution for Doctor consultation.
YES....both Acetaminophen and Ibuprofen are designed to reduce swelling in mussels and joints....Codeine is strictly for pain.


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