what do you know about prenatal diagnosis?

Question:

especially sickle cell disease. should AS marry AS?

Answers:
Sickle cell anemia is inherited as an autosomal recessive trait. This means that in order for a child to have sickle cell in its full blown form, (s)he must inherit the trait from BOTH parents. If two carriers of the trait marry, these are the odds:

Both parents are Ss, so Ss crossed with Ss yields a 50% chance that a child will be a carrier (have sickle cell trait), a 25% chance that a child will be normal (not have any sickle cell at all in their genes), and a 25% chance that a child will have sickle cell disease.

If a person with sickle cell marries a normal person, then all of their children will be carriers (have the trait).

If a person who is a carrier marries a normal person, then 50% of the children will have the trait and 50% will be normal.

If a person who is a carrier marries a person with sickle cell, 50% of the children will be carriers, and 50% will have the disease.

In the unlikely case that two people with sickle cell disease marry, then ALL of their children will have the disease.

Note that these numbers apply to EACH pregnancy: no matter what the outcome of each child, the chances are still the same for any siblings. So the only way a child can inherit the actual sickle cell disease is if the trait is carried by both parents or at least one of them actually has the disease.

Other Answers:
If you both have sickle cell trait or disease the is a 99.99 percent chance your baby will have the disease.

the best answer you will get is by asking a doctor

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what do you know about prenatal diagnosis?

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