I am taken prescribed course of clindamycin 150g what dose this do?

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staphylococcal bone and joint infections, peritonitis; endocarditis prophylaxis [unlicensed indication],
Cautions discontinue immediately if diarrhoea or colitis develops; hepatic impairment (Appendix 2); renal impairment; monitor liver and renal function on prolonged therapy and in neonates and infants; pregnancy (Appendix 4); breast-feeding (Appendix 5); avoid rapid intravenous administration; avoid in porphyria (section 9.8.2); interactions: Appendix 1 (clindamycin)

Contra-indications diarrhoeal states; avoid injections containing benzyl alcohol in neonates (see under preparations below)

Side-effects diarrhoea (discontinue treatment), abdominal discomfort, oesophagitis, nausea, vomiting, antibiotic-associated colitis; jaundice; leucopenia, eosinophilia, and thrombocytopenia reported; rash, pruritus, urticaria, anaphylactoid reactions, Stevens-Johnson syndrome, exfoliative and vesiculobullous dermatitis reported; pain, induration, and abscess after intramuscular injection; thrombophlebitis after intravenous injection

Dose
By mouth, 150–300 mg every 6 hours; up to 450 mg every 6 hours in severe infections; child, 3–6 mg/kg every 6 hours

Counselling Patients should discontinue immediately and contact doctor if diarrhoea develops; capsules should be swallowed with a glass of water.

By deep intramuscular injection or by intravenous infusion, 0.6–2.7 g daily (in 2–4 divided doses); life-threatening infection, up to 4.8 g daily; single doses above 600 mg by intravenous infusion only; single doses by intravenous infusion not to exceed 1.2 g; child over 1 month, 15–40 mg/kg daily in 3–4 divided doses; severe infections, at least 300 mg daily regardless of weight

Clindamycin has only a limited use because of serious side-effects. Its most serious toxic effect is antibiotic-associated colitis which may be fatal and is most common in middle-aged and elderly women, especially following operation. Although antibiotic-associated colitis can occur with most antibacterials it occurs more frequently with clindamycin. Patients should therefore discontinue treatment immediately if diarrhoea develops.

Clindamycin is active against Gram-positive cocci, including penicillin-resistant staphylococci and also against many anaerobes, especially Bacteroides fragilis. It is well concentrated in bone and excreted in bile and urine.

Clindamycin is recommended for staphylococcal joint and bone infections such as osteomyelitis, and intra-abdominal sepsis.

Clindamycin is used for prophylaxis of endocarditis in patients allergic to penicillin [unlicensed indication],

Oral infections
Clindamycin should not be used routinely for the treatment of oral infections because it may be no more effective than penicillins against anaerobes and there may be cross-resistance with erythromycin-resistant bacteria. Clindamycin can be used for the treatment of dentoalveolar abscess that has not responded to penicillin or to metronidazole.

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I am taken prescribed course of clindamycin 150g what dose this do?

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