what are the five main homeostatic functions of the kidney?


Question:
preferbly legit answers from a .org website?
any advice on which sites to check out?

Answers:
1)they remove wastes that form during cellular metabolism, as well as toxic and non toxic substances 2)maintain appropriate concentration of water and ions 3)regulate volume of blood and interstitial fluids by controlling ion excretion 4)appropriate balance of hydrogen ions and hydroxyl ions in the blood 5)maintains the pH of the body fluids for chemical reactions.

Other Answers:
not quite sure.try to filter the blood, salt reabsorbtion, to trigger the brain's osmoreceptors to get more water into the body (this is why you get thirsty).

any good biological website should have this info. Produces erythropoetin - to stimulate RBC growth
Activates vitamin D
excretes phosphorus
filters and removes toxins
regulates blood volume

I think those are basically it.. check out www.kidney.org or read up on the K/DOQI guidelines Homeostasis
Acid-Base Balance

The kidneys regulate the pH, mineral ion concentration, and water composition of the blood.

By exchanging hydronium ions and hydroxyl ions, the blood plasma is maintained by the kidney at pH 7.4. Urine, on the other hand, becomes either acidic at pH 5 or alkaline at pH 8.

The pH is maintained through four main protein transporters: NHE3 (a sodium-hydrogen exchanger), V-type H-ATPase (an isoform of the hydrogen ATPase), NBC1 (a sodium-bicarbonate cotransporter) and AE1 (an anion exchanger which exchanges chloride for bicarbonate). Due to the polar alignment of cells in the renal epithelia NHE3 and the H-ATPase are exposed to the lumen (which is essentially outside the body), on the apical side of the cells, and are responsible for excreting hydrogen ions (or protons). Conversely, NBC1 and AE1 are on the basolateral side of the cells, and allow bicarbonate ions to move back into the extracellular fluid and thus are returned to the blood plasma.
Check the site below for all you need to know




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