what is that in a tobacco which makes cigarette smoking, pan chewing etc tough to leave?

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Tobacco contains the alkaloid nicotine, a powerful neurotoxin that is particularly harmful to insects. All means of consuming tobacco result in the absorption of nicotine in varying amounts into the user's bloodstream, and over time the development of tolerance and dependence. Absorption quantity, frequency and speed seem to have a direct relationship with how strong a dependence and tolerance, if any, might be created. A lethal dose of nicotine is contained in as little as one half of a cigar or three cigarettes; however, only a fraction of the nicotine contained in these products is actually released into the smoke, and most clinically significant cases of nicotine poisoning are the result of concentrated forms of the compound used as insecticides. Other active alkaloids in tobacco include harmala alkaloids.

Nicotene

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what is that in a tobacco which makes cigarette smoking, pan chewing etc tough to leave?

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