Can you still have Lupus if all test came out posive but DNA came out Neg?
Question:
Answers:
Yes - particularly if you have the clinical features (particular rash, joint aches and pains, anaemia, pericarditis, kidney problems ... etc.)
The various antibody tests are all testing for antibodies to this and that ... smooth muscle, double stranded DNA, cell nucleus, microsomes, etc...
You can have lupus if many of the antibodies are present, but one (in your case anti-dsDNA antibody) comes out negative.
Anti-dsDNA antibody is highly specific, but only 70% sensitive.
That means that if you HAVE it, there is a very good chance you have lupus.
If you don't have it, you might have something else, but it might still be lupus.
Yes, I've had it for 3 yrs. and my test results are similar.
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