What vitamin are you deficiant in with Progressive Bulbar Paulsy?


Question:
It is said that PBP is a "vitamin dependent" Disease and that massive doses of a certain vitamin will begin to reverse it

Answers:
Epidemiology
Onset age 50-70 years


Pathophysiology
Subtype of Amyotrophic Lateral Sclerosis (ALS)
Cranial Nerve motor nuclear atrophy, glial overgrowth
Cranial Nerve 5
Cranial Nerve 7
Cranial Nerve 9
Cranial Nerve 10
Cranial Nerve 12
Subcortical involvement of corticobulbar tracts


Symptoms
Drooling
Difficult chewing
Dysphagia
Dysarthria
Nasal regurgitation


Signs
Arm and leg spasticity
Hyperactive reflexes
Ophthalmoplegia
Fasciculation of Tongue and lip muscles
Emotional lability


Differential Diagnosis
Acute bulbar paralysis
Acute CNS vascular lesion (hemorrhage or thrombosis)
Acute Bulbar Polioencephalitis
Chronic bulbar paralysis
Syringobulbia
Multiple Sclerosis


Course
Progresses to Aspiration Pneumonia, respiratory arrest
Death in 1 to 3 years from onset

Comment added by Richard W. Webb on 2/27/04
I'm being treated at UCSF. I've been told that Progressive Bulbar Palsy (my diagnosis) is "onset ALS". Go to this web site for information, hope, and help. Print out all 21 pages and study it. I've tripled the recommended dose of Vitamin E.

http://www.lef.org/protocols/prtcls-txt/t-prtcl-008.html

Good Luck to your dad,

Richard Webb

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