rhinocerebral mucormycosis,ca. agent,therapy,c.

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Mucor is a fungus which is enviromental, frequently comtaminates air ducts in hospitals and infects debilitated patients in intensive care units by that route. The spores are inhaled, set up housekeeping in the sinuses where they supersporulate. At this point its a fair fight between the fungus and the immune system, which, when healthy, can usually take care of the fungus. But those with diabetes, poor immunity, like prematures, and some surgical patients are not up to the fight. For them the fungus wins, starts directly invading blood vessels from the nose to the brain.

Treatment is the aggressive control of underlying disease, intravenous amphotericin B, and aggressive surgical debridement, often repeatedly, of all devitalized tissue. Mucor often leaves a hole in the face if patients survive it.

Control involves suppression of spores in enviroments where most debilitated patients stay, and healthy suspicioun and early diagnosis of any facial swelling in diabetics of hospitalized patients.

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http://www.bcm.edu/oto/grand/07_13_00.htm

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rhinocerebral mucormycosis,ca. agent,therapy,c.

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