Is lachenplanus curable. if so Pl Tell the treatment or contacts for?
Question:
Answers:
#1 its lichen not lachen
#2 its treatable not curable.(the skin problem could be made better but the disease cannot be removed. it might go away by itself)
#3 steroids are the mainstay of treatment and you need a doctors prescription for that.
: Lichen planus (LP) is a pruritic, papular eruption characterized by its violaceous color; polygonal shape; and, sometimes, fine scale. It is most commonly found on the flexor surfaces of the upper extremities, on the genitalia, and on the mucous membranes. LP is most likely an immunologically mediated reaction.
Causes: The exact cause of LP is not known. The pathogenesis of LP is immunologically mediated. Whether the foreign antigen is a virus or a drug is not known. Langerhans cells process antigens, which are then presented to T lymphocytes. This stimulated lymphocytic infiltrate is epidermotropic and attacks keratinocytes. During this lymphocytotoxic process, the keratinocytes release cytokines that attract more lymphocytes. This process has been referred to as the lichenoid tissue reaction. Also, recent studies reveal a disruption in the epithelial anchoring system.
Some patients with LP have a positive family history. It has been noted that affected families have an increased frequency of human leukocyte antigen B7 (HLA-B7). Others have found an association between idiopathic LP and human leukocyte antigen DR1 (HLA-DR1) and human leukocyte antigen DR10 (HLA-DR10); thus, LP may be influenced by a genetic predisposition.
Medical Care: LP is a self-limited disease that usually resolves within 8-12 months. Mild cases can be treated symptomatically with antihistamines and fluorinated topical steroids. More severe cases, especially those with scalp, nail, and mucous membrane involvement, may need more intensive therapy
The first-line treatments of cutaneous LP are topical steroids, particularly class I or II ointments. A second choice would be systemic steroids for symptom control and possibly more rapid resolution. Many practitioners prefer intramuscular triamcinolone 40-80 mg every 6-8 weeks. Oral acitretin has been tried with some success. Many other treatments are of uncertain efficacy because of the lack of randomized controlled trials. For LP of the oral mucosa, topical steroids are usually tried first. Topical and systemic cyclosporin has been tried with some success. Other options include oral or topical retinoids. Even with these effective treatments, relapses are common.
Psoralen with ultraviolet light A (PUVA) therapy for 8 weeks has been reported to be effective. Risks and benefits of this treatment should be considered. PUVA is carcinogenic. Long-term risks include dose-related actinic degeneration, squamous cell carcinoma, and cataracts. A phototoxic reaction with erythema, pruritus, phytophotodermatitis, and friction blisters could occur.
UV-A therapy combined with oral psoralen consists of oral psoralen (0.6 mg/kg), 1.5-2 hours before ultraviolet light, which usually starts at 0.5-1 J/cm2 and is increased by 0.5 J/cm2 per visit. Use of topical ointment at the time of receiving UV-A treatment may decrease the effectiveness of PUVA. Precaution should be taken for persons with a history of skin cancers or hepatic insufficiency
Other Answers:
LONGER TONGUE,
There is no known cure for skin lichen planus, but treatment is often effective in relieving itching and improving the appearance of the rash until it goes away. Since every case of lichen planus is different, no one treatment does the job.
Topical corticosteroids are very useful. Antihistamines may be prescribed to relieve itching. Extensive cases may require the use of oral corticosteroid (cortisone, prednisone) for a number of weeks. This usually shortens the duration of the outbreak.
For severe cases powerful treatments include photo chemotherapy light treatment (PUVA), the retinoids drugs (Soriatane and Accutane), Neoral and Plaquenil.
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