is iganephropathy heriditary?
Question:
Answers:
This is what is currently known:
Greater than 90% of IgA nephropathy is not familial (in other words, there are no other family members with the disease).
There appears to be a familial clustering of IgA nephropathy which shows strong family predisposition in about 10% of cases, with this being more common in some specific regions or in families from those regions. In the U.S., these include Kentucky and parts of the Southeast. In other parts of the world, familial clustering of IgAN seems to be more common in Southern France and Italy.
In addition to the regional-based familial clustering, IgAN is known to be more common in some specific ethnic groups (although it does not necessarily run in families). IgAN is most common in people of Asian ethnicity (oriental), followed by Hispanics and then Caucasians (seems to be relatively more common among French). It is least common in African Americans. IgAN is also more common in American Indians than it is in whites.
Other Answers:
".do not know what causes IgA deposits in the glomeruli. But, since IgA nephropathy may run in families, genetic factors probably contribute to the disease."
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