Diabetes–Away from needle?


Question:
NEW YORK (Reuters Health) Jul 13 - Inhaled human insulin (Exubera) provides glycemic control comparable to that with subcutaneous insulin with only minor, reversible effects on pulmonary function, according to findings published in the June issue of The Journal of Clinical Endocrinology & Metabolism.
http://www.health-sky.com/html/excited-n...

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Answers:
Inconvenient - requires a large apparatus.
Dosing somewhat inprecise - a problem for Type 1's.
Long-term pumonary effects unknown.

For inadequately controlled Type 2's who are needle-phobic it may be just the thing.
yes, there is now an inhaled insulin... i would waite awhile before trying this though! i think it is better for type 2's not type 1's.
Not totally. Longterm effects need to be evaluated.
Exubera is human insulin derived from rDNA. It is a quick acting insulin so it is used to control the post-prandial (after meals) glucose excursion. From an academic standpoint it may not be quite as good as the analog insulins but all of these require injection. Exubera is expensive and I believe this to be its major drawback. In addition most people on pre-prandial insulin are on basal analog insulin. Since basal and rapid acting insulin are available premixed a person may require only 2 injections a day as opposed to 1 injection of basal insulin and multiple oral inhalations of Exubera. I am not a frequent user of Exubera but it is an excellent drug and a welcome addition to the pharmacologic treatment of diabetes. I hope that your question does not imply that you have diabetes. If you do however most physicians have information kits and demonstrator devices of Exubera.
It is very bulky and expensive. There is no long acting verson, so if you need to take long acting insulin (lantus, L, NPH) then you would still need to take shots. Because if this, it is probably going to be better for type 2 diabetics who are on the verge of starting insulin therapy.

There are problems with patients who are involved with smoking. However, first and second hand smoke seem to have opposite effects in preliminary studdies.
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